September 26 , 2012
Psych 2E03: Sensory Processes
Introduction to Vision
Principle of brainstem auditory evoked response
- far field responses (<25ms): brain stem auditory evoked response, 5 waves
- near-field responses (>25ms): cortex later wave
- anything wrong in the conduction pathway will affect near responses
Brain-stem Auditory Evoked Responses
- initial 2 waves: auditory nerve, far field
- 3-5: brain stem, far field
- 6: cortex, near field
Typical Evoked responses to a meaningful stimulus
- P1, P2, P3 etc. = 1 , 2 , 3 , etc. positive waves
- N1, N2 = 1 2 negative waves
- Note: the polarity may vary with reference to the electrode position. It is not
important. Latency and amplitude of the peaks are important
P300 a marker for Schizophrenia and Bipolar disorder - P300 latencies: patients>relatives>control, takes a longer time then it shouls,
latency prolonged and amplitude are reduced
- P300 amplitudes: contrl>relatives> patients
- A similar trend has been even more consistently reported in schizophrenia
literature
N170, N250, P300-600
- shown picture of a face, no matter whose face it is you will see N170
- if face belongs to face you’re familiar with N170 and N250
- name of face, depending on how familiar you are P300-600, simpler more
P300, complex P600, probably will also get the responses at N170 and N250
What type of ERp may seeing this conflicting/counter-intuitive picture evoke
- N600, long latency, longer processing time
- Depending on how long the latency is we are using more complex processes
- Conflict: longer latency
Skin conductance test
- P300/N600
- Skin detection signal to test
Functional MRI (fMRI)(MRI=Magnetic resonance imaging)
- MRI detects levels of deoxyhemoglobin in the blood and bold images (blod-
oxygen-level dependant images)
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