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CA (620,000)
McMaster (50,000)
PSYCH (6,000)
PSYCH 1XX3 (1,000)
Joe Kim (1,000)
Lecture 9

PSYCH 1XX3 Lecture Notes - Lecture 9: Malar Rash, Pernicious Anemia, Stomach Cancer


Department
Psychology
Course Code
PSYCH 1XX3
Professor
Joe Kim
Lecture
9

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Autoiue Disease’s
Disease
Auto-antibodies
Features
SLE
Anti-sm
Anti Ro
Anti-LA
Anti-dsDNA
F:M = 9:1
Serositis, Oral ulcers, Arthritis,
Photosensitivity, Blood changes, Renal
involvement, ANA, Immunological changes,
Neuro stuff, Malar rash, Discoid rash
Drug-induced lupus
Anti-Histone
Procainamide
Hydralazine
Isoniazid
Clindamycin
Sjogrenʼs Syndrome
Ant-LA
Anti-Ro
RA
Anti-CCP
Diffuse Scleroderma
Anti-SCL 70
CREST + Pulmonary fibrosis, Renal disease,
Polyarthritis, Myopathy/muscle atrophy
Limited
Scleroderma/CREST
Anti-centromere
Calcinosis, Raynauds Phenomenon,
Osephageal dismotility, Sclerodactyly,
Telangectasia
Dermatomyositis/
polymyositis
Anti-Jo-1
Wegnerʼs
granulomatosis
C-ANCA
Pernicious anaemia
90% antiparietal cell
antibodies
50% antiIF antibodies
Autoimmune attack on parietal cells - atrophic
gastritis & lack of intrinsic factor
serum vit. B12
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