BIOL 3500 Lecture 4: 4 cartilage

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Cartilage and bone: cartilage has a firm pliable matrix that resists mechanical stresses, bone matrix is one of the hardest tissues of the body. Both have cells that are specialized to secrete the matrix in which, subsequently, the cells become trapped. Both are involved in supporting the body: most of the long bones of the body are formed first in the embryo as cartilage. Chondrocytes: spaces within the ecm called lacunae, secrete ecm. Most cartilages have a dense ct covering = perichondrium, which contains the vascular supply and stem cells (chondroblasts) Depending on composition of matrix: thin fibers of type ii collagen dense, coarse type i collagen fibers type ii collagen and abundant elastic fibers. Bluish-white and translucent (greek word hyalos, glass) type ii collagen firm, gel-like consistency. flexible and resistant to compression --> functions as a shock absorber smooth surface permits almost friction-free movement of the joints of the body.

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