HKR 2311 Lecture 4: HKR2311 - Unit 4
14 Feb 2017
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Document Summary
Muscle types: there are three types of muscle tissue: Microanatomy of skeletal muscle tissue: some important characteristics of skeletal muscle fibers that distinguish them from other fibers are: Multinucleated (each fiber contains hundreds of nuclei: a clear understanding of the following features of skeletal muscle fibers are needed: Contraction of skeletal muscle: there are a number of events that take place for a contraction to occur. Huxleys sliding filament theory, the nine steps are as follows: Depolarization at the synapse (acetylcholine from the synaptic terminal travels across the synaptic cleft to alter the permeability of the sarcolema) Wave of depolarization (na+, k+) travels along the membrane and down the t- tubules into the sarcoplasmic reticulum (sr) Ca++ attaches to troponin, resulting in a reconfiguration. Troponin reconfigures tropomyosin, opening an active site on the actin. The myosin head attaches to the actin active site. With atp, the myosin head moves or slides (the breakdown of atp into adp and.
