ADMN2307 Lecture Notes - Lecture 6: Ke Family, Developmental Coordination Disorder, Cerebellum
11 Dec 2015
School
Department
Course
Professor
Document Summary
Gene and environment interactions depend on environmental variables. Animal models of epigenetic modifications are extended to humans (but. Experience and genes on high cortisol levels and high anxiety difficult) Life style factors that contribute to mortality (uk whitehall study) Huge proportion of mortality that can"t be explained (maybe the early years of your life) Effect of early experience biological embedding with early experience being most important as there is no amount of experience after this period that can overturn this early experience. Changes later in life will not have as much influence on the genes as much as the early changes that had occurred early on. Methyl groups and histones can make the dna inaccessible if tightly bound. Methyl groups prevents dna transcription around histones. Epigenetic regulators (histone modifications) can unwind and make the. Dna accessible to be making them partially accessible and a possibility for transcription.
