ANAT 216 Lecture Notes - Lecture 13: Common Hepatic Duct, Common Bile Duct, Cystic Duct
28 Apr 2018
School
Department
Course
Professor
ANAT 216 week 5 lecture 2
Biliary
ducts and
gull
bladder
Bile leaves liver via R and L hepatic ducts
common hepatic duct cystic duct to
gallbladder OR common bile duct to ampulla
of vater encircled by hepatopancreatic
sphincter of Oddi connected to duodenum
Cystic had a mucosal spiral fold keeping
lumen open
Hepatocytes secrete bile into canaliculi
extending out from central vein bile
ductules which carry bile to nearest portal
triad
Gall
bladder
Located in fossa on R hepatic lobe, muscular
sac that stores and concentrate bile not
immediately required for digestion, release
bile into duodenum (controlled by CCK)
- No CCK= Oddi remains closed, bile
flows into cystic duct and stored in
GB
- CCK= Oddi relaxes and GB wall
contracts so bile flows into cystic
duct CBD duodenum
3 parts: fundus, body, neck supplied via cystic
artery
Gall
bladder
histology
Simple columnar w apical microvilli, no muscular mucosa and little submucosa,
muscularis externa is scattered, perimuscular fibrous tissue layer, outer adventitia
Pancreas
Ductless gland, retroperitoneal, head lies in
concavity of duodenum body and tail reach
twrds spleen
Pancreatic duct (WIrsung) fuses w bile duct at
hepatopancreatid ampulla and empties into
duodenum
Acini (secrete water, ions, enzymes)
connected by ductsinterlobular ducts
pancreatic duct common bile duct
Pancreas
histology
CT septa sep it into lobules, 99% exocrine gland and 1% endocrine gland (Islets of
Langerhans)
Exocrine- tubuloalveolar gland, acini (blind pockets lined w simple cuboidal) which
empty into small ducts main ducts,
Endocrine- islets scattered among acini, endocrine cells
- Alpha cells- glucagon
- Beta cells: insuling
- Delta: somatostatin/GH
- PP (F): pancreatic polypeptides
acinar cells of smallest ducts secrete pancreatic juice (enzymes, HCO3)
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Document Summary
Bile leaves liver via r and l hepatic ducts common hepatic duct cystic duct to gallbladder or common bile duct to ampulla of vater encircled by hepatopancreatic sphincter of oddi connected to duodenum. Cystic had a mucosal spiral fold keeping lumen open. Hepatocytes secrete bile into canaliculi extending out from central vein bile ductules which carry bile to nearest portal triad. Located in fossa on r hepatic lobe, muscular sac that stores and concentrate bile not immediately required for digestion, release bile into duodenum (controlled by cck) No cck= oddi remains closed, bile flows into cystic duct and stored in. Cck= oddi relaxes and gb wall contracts so bile flows into cystic duct cbd duodenum. 3 parts: fundus, body, neck supplied via cystic artery. Simple columnar w apical microvilli, no muscular mucosa and little submucosa, muscularis externa is scattered, perimuscular fibrous tissue layer, outer adventitia. Ductless gland, retroperitoneal, head lies in concavity of duodenum body and tail reach twrds spleen.
