BCHM 102 Lecture Notes - Lecture 2: Arginine, Asparagine, Lysine
2 Dec 2016
School
Department
Course
Professor
Document Summary
Learning outcomes: define proteins and recognize importance in cell and body, classify 20 common amino acids. Identify common structure and properties of amino acids. Typically, between macromolecules and do not involve sharing a pair of electrons. They are critical in maintaining the 3d structure of large molecules such as proteins and nucleic acids. Electrostatic/ionic/salt-bridges (charge-charge: can be easily removed - not a very strong connection, held together not by bonds, but by opposite charges, ex. Van der waals (diploe-dipole: nonspecific interactions resulting from the momentary random fluctuations in the distribution of the electrons of any atom, weak attraction. Hydrogen bond: essential for protein folding, most important (strong) Interaction between an h-bond donor (+ve) and an h-bond acceptor (-ve: +ve charged h+ interacts with the -ve charged lone pair of electrons, ex. Nh3 --> nitrogen pulls h"s electrons away, and h interacts with another nitrogen"s lone pair of electrons (looks like a christmas tree) Hydrophobic/hydrophilic (molecules in water: hydrophilic (water loving)
