BCHM 218 Lecture Notes - Lecture 19: Nucleosome, Histone H2A, Giemsa Stain
11 Apr 2018
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Extra oh on c2 of rna makes it less stable so it can be enviro responsive. Nitrogenous base adenine adenosine nucleoside datp for dna or atp for. Chargaffs rule: base comp of dna varies from species to species, dna samples from diff tissues of the same species have the same base comp, dna base comp dn change w age, nutritional state or enviro. In all dnas, a=t, g=c (at longer + easier to compress/pack) Rosalind franklin- x ray crystallography to identify dimensions of dna helix and water content of dna. Crick- major groove used for binding proteins, antiparallel written in 5-3 direction, 10. 5bp=one turn sens strand 5-atgtct-3 antisense 3-tacaga-5 (non-coding, template) Long-term storage of genetic info: base seq for one strand defines seq of other template for dna rep: fidelity- can be sep + used as temp coding for proteins + functional rnas.
