BIOL 102 Lecture Notes - Lecture 18: Noncoding Dna, Ribosomal Rna, Genome Size

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By 2000 each research centre working on hgp was sequencing 1000 base pairs per second 24/7. Whole-genome shotgun approach starts with the cloning and sequencing of. Metagenomics approach: where dna from a group of species is collected from an environmental sample and sequenced, sequencing on broad scale. Allows for study of whole sets of genes and their interactions, and comparison of genomes from different species. As of july 2013, genbank included sequences of 165 million fragments of genomic dna, totalling 153 billion base pairs. Gene annotation: identify all protein-coding genes in the sequences and ultimately their functions. Proteomics: study of the full protein sets (proteomes) encoded by genomes. Proteins carry out most of the activities of the cell, we study when and where proteins are produced in an organism, as well as how they interact in networks. Systems biology: aims to model the dynamic behaviour of whole biological systems based on the study of the interactions among the system"s parts.

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