BIOL 103 Lecture Notes - Lecture 4: Carbonic Anhydrase, Pulmonary Circulation, Thrombin

• School: Queen's University
• Department: Biology
• Course: BIOL 103
• Professor: Virginia K Walker

Document Summary

Platelets: filled with microfilaments and actin: megakaryolites. The platelets with change their shape and move via their actin. The hormone prostaglandin helps the platelets adhere to one another. Cycloxygenases makes prostaglandin (cox: asprin can inhibit cox by putting an acetyl group on cox. Platelets that have adhered to each other create a platelet factor. Platelet factor is necessary for taking prothrombin (zymogen) and turning it into thrombin. 13 other factors and calcium also help with this transition. Kelating agent can help the blood stay liquid by binding up all the calcium so that it cannot convert prothrombin to thrombin. Responsible for the conversion of fibrinogen to fibrin: mo(cid:396)e (cid:272)al(cid:272)iu(cid:373) is (cid:396)e(cid:395)ui(cid:396)ed to (cid:271)i(cid:374)d the fi(cid:271)(cid:396)i(cid:374) (cid:373)ole(cid:272)ules togethe(cid:396) fo(cid:396)(cid:373)i(cid:374)g a (cid:862)(cid:374)et(cid:863) a(cid:374)d (cid:272)at(cid:272)hi(cid:374)g (cid:396)ed (cid:271)lood (cid:272)ells a(cid:374)d fo(cid:396)(cid:373)i(cid:374)g a (cid:373)ature clot. Fibrinogen becomes fibrin via thrombin and releases fibrinopeptides. How to kill rats: warfarin poison, vitamin k reductase recognizes vitamin k.