BIOL 103 Lecture Notes - Lecture 4: Hematocrit, Macrophage, Mhc Class I

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Whole blood: transport of gases, environment to tissues, transport of nutrients and waste products between tissues, immune system, plasma 50-60% (made up of 90% water) has proteins, cell components (white & red blood cells & platelets) Platelets are essential for clotting: injury ruptures blood vessel, platelets stick to each other and to collagen fibers acting as a, fibrin forms a mesh that traps cells and platelets forming a. Have no nucleus and are shaped with a dimple (increase surface plug clot area) Hemoglobin has an iron center that binds to oxygen, it"s a tetramer (made up of 4 subunits) Atmospheric pressure = pressure on body surface. Atmospheric pressure = sum of the partial pressure: p02 = 0. 21 * 760mmhg (sea level) = 160mmhg. Diffusion across cell membranes is driven by partial pressure (cid:1) (cid:1) (cid:1) Co2 can be carried by the plasma , some by the red blood cells but not by hemoglobin. A. a change - glutamic acid --> valine.

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