BIOL 103 Lecture Notes - Lecture 5: Human Leukocyte Antigen, Cytotoxic T Cell, Cell-Mediated Immunity
28 Apr 2016
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Add one to a few amino acids adding variability. If these are overlapping, and we"ve lost some, this will be a little shorter. Hyper mutation enzyme which will dominate cytosine and this will have to be repaired to a thymine v*, increasing variability by creating mutations in that variable area. Not all that important for us because we have so many variable regions. Chickens depend on this because they have few variable regions. We have 2 chromosomes, why did we draw it as a single. Allelic exclusion we have 2 chromosomes, and the first one assembled will be used to make the light chain. 2 different kinds of j regions, 2 assemblies, 2 loops splicing mrna. In a particular immature b lymphocyte the 300th v region is join is joined to the 3rd j region. Draw the primary transcript and show the processing involved to make a mature mrna corresponding to the light chain of the mature b lymphocyte.
