BIOL 334 Lecture Notes - Lecture 23: Vacuole, Starch, Hexokinase
2 Dec 2016
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Document Summary
The central catabolic pathway of all cells (its also amphibolic) Most extensively studied pathway in terms of comparative biochemistry (also a huge focus for cancer and tumour research) Provides excellent example of how a ubiquitous metabolic pathway can show significant differences in its structure, control, and compartmentation in different phyla. (i. e. , the adaptability of metabolism) Shows how role of atp/adp system in biological energy transduction can be partially replaced or augmented by the ppi/pi system. Gl(cid:455)(cid:272)ol(cid:455)ti(cid:272) (cid:396)egulatio(cid:374) i(cid:374)(cid:448)ol(cid:448)es all (cid:373)e(cid:272)ha(cid:374)is(cid:373)s of (cid:858)fi(cid:374)e co(cid:374)t(cid:396)ol(cid:859) Glycolysis is directly involved in many biochemical adaptations to environmental extremes (e. g. ability of many species to acclimate to anoxia, freezing, desiccation, salinity stress, starvation, nutrient limitation, and hibernation includes glycolytic control, and/or accumulation of glycolytic end products) Overall reaction: (for classical glycolysis as depicted above): glucose + 2adp + 2pi + 2nad+ 2 pyruvate + 2atp + 2nadh, but with o2 get 2atp/nadh (via external dehydrogenase of mitochondrial e. t. c), overall we get:
