HLTH 315 Lecture Notes - Lecture 10: Margaret Hamilton (Scientist), Diabetes Care, Cardiovascular Disease

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Hamilton, m. t. , hamilton, d. g. , & zderic, t. w. (2007). Role of low energy expenditure and sitting in obesity, metabolic syndrome, type 2 diabetes, and cardiovascular disease. Sedentary behavior: daily sitting time/low nonexercise activity levels may have a significant direct relationship with mortality, cv disease, type 2 diabetes, metabolic syndrome risk factors, obesity. Bed rest: consequences: several physiological responses. Translational studies needed at multiple levels, ranging from cellular research determining whether there are plausible mechanisms regulating risk factors to more epidemiological research identifying clinical outcomes in diverse populations. Healy, g. n. , dunstan, d. w. , salmon, j. , cerin, e. , shaw, j. e. , zimmet, p. z. , & owen, n. (2008). Total sedentary time is associated with obesity, abnormal glucose metabolism, and the metabolic syndrome. In addition to effects of total sedentary time, the manner in which it is accumulated is also important. Increased breaks in sedentary time were beneficially associated with waist circumference.

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