KNPE 125 Lecture Notes - Lecture 28: Baroreflex, Squatting Position, Sarcolemma
Document Summary
Map = co/tvc or map = co x tpr (total peripheral resistance) Total vascular conductance and distribution of blood flow. Blood distributed to the body based on o2 requirements. Arterial system must control distribution of blood flow. Resting blood flow cardiac output = 5l/min vs. The arterial system maintains map and controls distribution of blood flow. Arterioles are small vessels that supply blood to organs within our tissue beds. Arterioles are able to change size depending on demand of the tissues. Arterioles play a major role in regulating map. Arterioles are the main site for control of local blood flow. Change in diameter will have the largest change in flow to the 4th power. In resistance vessels (arterioles), smooth muscle on vessel walls adjusts arteriole diameter. Vasoconstriction smooth muscle contracts and resists blood flow: sympathetic nerve activity on smooth muscle, central control message from cns.