MICR 221 Lecture Notes - Lecture 28: Cytoskeleton, Nuclear Membrane, Double-Stranded Rna Viruses

• School: Queen's University
• Department: Microbiology and Immunology
• Course: MICR 221
• Professor: Jarrell

Document Summary

+ rna virus: used to make which is used to make protein or + - strand where pol e(cid:374)coded at 5" e(cid:374)d (cid:373)ade first the(cid:374) (cid:373)rna (cid:373)ade usi(cid:374)g pol. Rna virus: for seg rna, - strand used to make + mrna strand and replicated for template use, non-seg rna uses rna pol encoded in genome and encode multiple genes. Ambisense rna viruses: - and + polarity, np makes capsid and so made right away, virus brings in pol used on strand and makes antigenomic s. Rna w opp polarity so other half can be translated (gp seg) Dsrna virus: - strand makes + mrna and + strand makes another strand, each vertex= rna pol, ssrna exits vertex ex. Step 6 assembly + egress: icosahedral capsids packaging of genome into capsid done via aeembly around virus genome preformed capsids. Helical nucleocapsids (rna viruses) viral genome coated w nucleocapsid protein during synthesis.