MICR 270 Lecture Notes - Lecture 2: B Cell, Cytotoxic T Cell, T Helper Cell
Document Summary
Non specifically during the early stages of response. Inflammation initiates these barriers of the innate system. Macromolecules that respond with complement proteins and cytokines. Complement proteins are dissolved in the blood in an inactive form. Cytokines are mediators are small proteins secreted by a broad range of cells. Major role of cell-to-cell communication and assist with immunity, inflammation. Molecular patterns on the surface of a cell is the immune system way of distinguishing a pathogen. The innate immune system have receptors that are able to recognize these patterns. Repeating sequences on the surface of a cell conserved across a class of microbes: damps- released from infected cells that bind to a range of. Also regulate mitochondrial function: recognition of prrs, activation of immune cells. Promote a pro-inflammatory and antimicrobial response, some assemble cytoplasmic signalling pathways causing an alteration in the gene expression within the cell, leading to cytokines, inflammation control.