Filter By
Filter Reset
Semester
Class Notes (1,044,551)
CA (598,665)
Queen's (19,037)
PATH (44)

Class Notes for Pathology and Molecular Medicine at Queen's University (page 2)

PATH 310 Lecture 11: Intro to Cancer II
Premium

Intro to Cancer II Oncogene Activated form leads to cancer Typically through overexpression or activating (dominant) mutation Tumour suppressor Loss of function leads to cancer Point mutations, deletions, gene rearrangemen...

Pathology and Molecular Medicine
PATH 310
Christine Hough
PATH 310 Lecture Notes - Lecture 13: Deoxyribose, Cytogenetics, Cytosine
Premium

Cortical bone Spongy bone Marrow ADAM. Cortical bone Spongy bone Marrow ADAM. Acute Leukemia: Clinical and Diagnostic Features Obtaining Bone Marrow Sample • Illinois bone marrow aspirate needle: p...

Pathology and Molecular Medicine
PATH 310
Christine Hough
PATH 310 Lecture Notes - Lecture 1: Gpvi, Thromboxane A2, Zymogen
Premium

Lecture 1. Hemostasis Hemostasis: The stopping of a flow of blood • This is the process which stops bleeding after injury to a blood vessel • Normally, our bodies want to make s...

Pathology and Molecular Medicine
PATH 310
Christine Hough
PATH 310 Lecture Notes - Lecture 3: Mutation, Covalent Bond, Hepatocyte
Premium

Hemophilia: Clinical Aspects After exposure of tissue factor and initiation of extrinsic pathway, factor 10 is activated to factor 10a Prothrobin is actiavte...

Pathology and Molecular Medicine
PATH 310
Christine Hough
PATH 310 Lecture Notes - Lecture 2: Antibody, Anaphylaxis, Endonuclease
Premium

PLASMA (Contains fibrinogen) WHITE BLOOD CELLS AND PLATELETS RED BLOOD CELLS BUFFY COAT SERUM (Minus fibrinogen) CLOT (Blood cells in fibrin clot) PLASMA (Contains fibrinogen) WHITE BLOOD CELLS AND PLATELETS RED BLOOD CEL...

Pathology and Molecular Medicine
PATH 310
Christine Hough
PATH 310 Lecture 15: Chronic Myeloid Leukemia
Premium

Scanned by CamScanner

Pathology and Molecular Medicine
PATH 310
Christine Hough
PATH 310 Lecture 16: HPV and Cervical Cancer
Premium

Scanned by CamScanner

Pathology and Molecular Medicine
PATH 310
Christine Hough
Pathology and Molecular Medicine
PATH 310
Christine Hough
PATH 310 Lecture Notes - Lecture 1: Von Willebrand Factor, Hemostasis, Thrombolysis
Premium

Lecture 1: Hemostasis • Blood vessels o Outer layer ▪ Fibroblasts o Then smooth muscle o Then endothelial cells • Fluidity of blood depends on o Intact vascular endothelium o Platelets in quiescent state o Regul...

Pathology and Molecular Medicine
PATH 310
Christine Hough
PATH 310 Lecture Notes - Lecture 6: Tunica Intima, Tunica Media, Endothelial Dysfunction
Premium

Lecture 6: Atherosclerosis  Complex  Influenced by environmental factors  Elastic and muscular arteries that are medium sized o Lose elasticity  Vessel thickening and stiffening  Increasing risk factors o El...

Pathology and Molecular Medicine
PATH 310
Christine Hough
PATH 310 Lecture Notes - Lecture 5: Thrombophilia, Venography, Embolization
Premium

Lecture 5: Thrombophilia • VTE venous thromboembolism • Distal has low risk of embolism • Proximal has high • VTE risk factors o Previous history o Family history (thrombophilia) o Immobilization o Surgery o Ca...

Pathology and Molecular Medicine
PATH 310
Christine Hough
PATH 310 Lecture Notes - Lecture 2: Thrombomodulin, Haemophilia B, Thrombin
Premium

Lecture 2: Hemophilia • Thrombin is the common pathway and principle enzyme in hemostasis o Converts fibrinogen to fibrin o And activates Factors V, VIII, XI, XIII for intrinsic pathway o When thrombin bound to throm...

Pathology and Molecular Medicine
PATH 310
Christine Hough
PATH 310 Lecture Notes - Lecture 4: Haemophilia, Thrombosis, Blood Plasma
Premium

Lecture 4: Hemophilia • Intrinsic pathway beginning o Enzyme: F9 o Cofactor: F8 o Substrate: F10 • 1-5% of F8 increased risk of hemophilia o >150% risk of thrombosis • Clinical complications o Spontaneous bleed...

Pathology and Molecular Medicine
PATH 310
Christine Hough
PATH 310 Lecture Notes - Lecture 8: Ejection Fraction, Cardiomyopathy, Treatment As Prevention
Premium

Lecture 8: Channeopathies and Cardiomyoathies • Structural and functional considerations for heart disease • Inherited cardiovascular diseases o Channelopathies ▪ Seemingly Normal ▪ Mutations in proteins of cardiac ...

Pathology and Molecular Medicine
PATH 310
Christine Hough
PATH 310 Lecture Notes - Lecture 3: Thrombomodulin, Fibrinolysis, Plasmin
Premium

Lecture 3: Thrombosis  Thrombin acts as enzyme for fibrinogen to fibrin  When in complex with thrombomodulin it inhibits this  Endothelium o Anticoagulants  Heparin sulfate  Binds anti-thrombin to accelerate i...

Pathology and Molecular Medicine
PATH 310
Christine Hough

Log In


OR

Don't have an account?

Join OneClass

Access over 10 million pages of study
documents for 1.3 million courses.

Sign up

Join to view


OR

By registering, I agree to the Terms and Privacy Policies
Already have an account?
Just a few more details

So we can recommend you notes for your school.

Reset Password

Please enter below the email address you registered with and we will send you a link to reset your password.

Add your courses

Get notes from the top students in your class.


Submit