PHAR 100 Lecture Notes - Lecture 2: Sympathetic Nervous System, Muscarinic Acetylcholine Receptor, Autonomic Nervous System

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Lesson 2. 1: physiological and pharmacological aspects of the central nervous system. Basic functions: recognize: identify changes in internal/external environments, process and integrate: perceive changes in environment, react: produce a response to the environment. Consists of central part (brain, spinal cord) and peripheral part (nerve fibres) Sensory nerves: carry messages from tissue to brain/spinal cord. Motor nerves: carry messages from brain/spinal cord to tissues. The spinal cord: carries sensory information from skin, muscles, joints and internal organs to brain, controls motor outflow to muscles, controls sensory input, controls reflex activity. The brain: receives and processes information. Initiates response: stores memories, generates thoughts and information, divided into 3 parts: Composed of grey matter (outside) and white matter (inside) Divided into two halves: left and right, connected by fibres. Subdivided into four lobes: occipital lobe: vision. Overall functions: sensory and motor coordination, mental processes, intelligence, memory, vision, judgement, thought, speech, emotions, consciousness. Can be stimulated/depressed by drugs: thalamus:

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