Class Notes (835,365)
Canada (509,137)
PHAR 100 (175)
Lecture

15stimulants2.pdf

5 Pages
96 Views
Unlock Document

Department
Pharmacology and Toxicology
Course
PHAR 100
Professor
Hisham Elbatarny
Semester
Fall

Description
Stimulant DrugsII Cocaine and AmphetaminesOutlinestimulantscocainepharmacokineticsmechanism of actionNeurotoxicityamphetaminesmechanism of actiondependence and Tolerancemethamphetaminenonamphetamine stimulantsStimulant Drugsaffect mental functioningaugment the action of neurotransmitters specifically DAincrease dopaminergic activity in areas of the brain involved inbehavioural reinforcement compulsive abuse drug dependency and drug cravingspositive effects euphoria alertness energy decreased appetitenegative effects irritability anxietyHistory of Cocainenaturallyoccurring substance obtained from the leaves of the coca treeindigenous to South Americanatives of Peru and Bolivia chewed the leaves of the coca tree for thousands of yearsreligious mystical euphoriant and medicinal purposesSigmund Freud advocated using cocaine to treat depression and chronic fatigue and used himselfcocaine became the main stimulant drug used in tonicselixirs CocaCola as we know it today Forms of Cocainecocaine hydrochloride white powder snortabsorbed through nasal mucosa 25100mgtimeinjected iv bc water solublecocaine base crackinhaled bc water insolubleforms a vapour when heated250mg1goccasionsignificant consequences to higher dose eg abuse dependencetoxicity
More Less

Related notes for PHAR 100

Log In


OR

Join OneClass

Access over 10 million pages of study
documents for 1.3 million courses.

Sign up

Join to view


OR

By registering, I agree to the Terms and Privacy Policies
Already have an account?
Just a few more details

So we can recommend you notes for your school.

Reset Password

Please enter below the email address you registered with and we will send you a link to reset your password.

Add your courses

Get notes from the top students in your class.


Submit