PHAR 100 Lecture Notes - Observer-Expectancy Effect, Antihistamine, Clinical Trial

• School: Queen's University
• Department: Pharmacology and Toxicology
• Course: PHAR 100
• Professor: Bill Racz

Document Summary

Drug advertising techniques: cob fud: catch audience (physician"s) attention, use of celebrities or authority to endorse products, fear, offering easy solution to problem, before-after technique, discredit drugs produced by other manufacture and praise your own. Phases of clinical trial: phase 1 study conducted in a limited number of healthy volunteers and effects are studied. Lesson a. 2 drug advertising, drug trials & placebo effects: phase 2 determine whether the drug is effective in treating the condition it is recommended for. Careful attention is paid to proof of concept/safety of the drug: phase 3 tested in larger number of people (~1000+). Safety and efficacy is studied: phase 4 ( postmarketing surveillance ) surveillance of the effects of drugs is required after the drug is released for general use as risks that are delayed or less frequent than. 1 in 1,000 administrations may be missed in the phase 3 trial.