PHGY 214 Lecture Notes - Lecture 30: Lusitropy, Cardiac Arrhythmia, Myocardial Infarction
Document Summary
Blood is reconditioned to keep comp stable (homeostasis) Reconditioning organs receive more blood needed for metabolic need. Blood flow can be adjusted to organs according to metabolic needs (skeletal muscle stim) 3 organs excusitely adjusted: heart+lung, brain and kidney. Brain is least able to tolerate disrupted supply. Kidneys need lots b/c it has to clean the blood. Skeletal muscle during exercise can have 4-5 time increase during exercise. Venous sys= has greatest blood supply reserve, can triple blood flow. Rate of blood flow thru a vessel is directly prop to the pressure grad and inversely porp to vascular resistance. F=p/r: f= flow rate, p= pressure grad, r= resistance of blood vessels. Primary pressure: aortic pressure is driving force. Pressure grad: pressure diff b/n the beginning and end of vessel, blood flows from high to low pressure. Viscosity of blood: thickness of blood, conc of rbc and conc of plasma proteins. Viscosity dn change but r does change!