PHGY 350 Lecture Notes - Lecture 9: Pituitary Stalk, Adrenal Tumor, Hypopituitarism

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Understand hormone regulation & how hormone measurements used to make differential diagnosis. Know difference between type 1, 2 diabetes (cause & complications) Familiar with all hypothalamic-pituitary axes and downstream functions/pathologies. Understand hormone regulation & how hormone measurements used to dx: specifically how to differentiate between primary and secondary pathology using negative feedback concepts. Appreciate that pituitary tumors can produce variety of pathologies. Multiple endocrine glands (many depending on how you define it) throughout body: secrete hormones directly into blood; act as receptors (often on other endocrine glands) and elicit a response (end r of the. H; or h stimulate other h to produce endocrine response). Hormones control many functions: metabolism; reproduction; fluid & electrolyte balance; growth. *hypothalamus pituitary gland secrete h stimulate other organs. Lh stimulates testosterone & progesterone (it has direct effect to for stimulate gonad to produce oocyte and sperm). Acth stimulates cortisol release from adrenal gland. Negative feedback: important aspect of hormone regulation.

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