PHGY 210 Lecture Notes - Lecture 32: Hyperglycemia, Adrenocorticotropic Hormone, Anterior Pituitary
Document Summary
There are times when endocrine glands over-secrete their hormones. This could be a problem but thank the lords bc we have negative feedback. When over-secretion occurs, the abundance of this hormone"s effect on the target tissue will inhibit its secretion. There is a lot of regulation that occurs with hormones. Insulin is a hormone that lowers blood glucose. You would think that insulin is released when blood glucose is high ( so it can act to lower it) low insulin when low blood glucose > high insulin when high blood glucose. Corticotrophin releasing hormone (crh) secretion from the hypothalamus causes the release of adrenocorticotropic hormone (acth) from the anterior pituitary. Acth causes the release of cortisol from the adrenal cortex. Cortisol can negatively feedback to inhibit the release of: crh from the hypothalamus, acth from the anterior pituitary. Question a person has high blood sugar! Insulin would try to correct this abnormality- so a high concentration would be present.