PHGY 210 Lecture Notes - Lecture 3: Muscarine, Cerebellum, Lisa Lopes

• School: Queen's University
• Department: Physiology
• Course: PHGY 210
• Professor: Christopher Andrew Ward

Document Summary

Cns for integration and initiating a response (sent through efferent division: efferent division: Graded potentials: receptor and generator potentials are graded potentials, amplitude/ duration dependent on strength and duration of stimulus. Receptor potential can trigger an ap by reaching the afferent nerve threshold. Receptor adaptation = regulation of response on receptors themselves. Phasic receptors: slow to non-adapting receptors, requires a constant stimulus, pain receptors, ap continuously produced during, rapid adapting receptors, stimulus does not always result in an ap, mechanoreceptors stimulus. Pain receptors are known as nociceptors, they are afferent nerve fibre endings (pain fibres) Consists of three types: mechanical nociceptors response to physical stimuli, thermal nociceptors response to temperature, chemical nociceptors response to internal and external noxious chemicals. Fast pain fibres: a-delta fibres, response to temperature, Ap reaches end of afferent pain fibre axon > releases neurotransmitter > substance p or glutamate > activation of ascending pathway > relays to the brain.