PHGY 350 Lecture Notes - Lecture 3: Rheumatoid Arthritis, Serous Fluid, Prostaglandin
16 Sep 2016
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Wound healing coagulation (continued from last lecture) We do not want a lot of fibrin just floating around in the bloodstream or else, blood would just randomly start clotting etc. Pt = prothrombin time from test to test, highly variable, depends on where the starting level is. Inr = international normalized ratio take control standard and made available to every lab and then going to test the prothrombin time: (pt vs control sample ratio) ** pt and inr measure extrinsic pathway (a)ptt = partial thromboplastin time. Hemophilia a (most common, defective factor viii) is an intrinsic disease, many varieties and severities. Von willebrand disease (most common clotting disorder) many different varieties and thus many different severities: rx: desmopressin (vasopressin analog) given nasally, von willebrand factor. Rigidity (very rigid, e. g. if there is scarring on a joint, makes joint more difficult to move) b. iii.
