BCH 361 Lecture 5: Glycogen Metabolism

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When energy is not required, glucose is stored as glycogen instead of undergoing metabolism. Glycogen is a long polymer of glucose that contains branching points. 1,4 glyosidic bonds: bond between c1 and c4. 1,6-glycosidic bonds: bond between c1 and c6 which gives branching point. Glycogen is stored in small cytoplasmic granules of liver cells and skeletal muscle cells. Liver cells: glucose lvl regulation, a process which is important bc brain cells depend solely on glucose molecules for atp = brain cells needs proper [glucose] in blood. Low blood [glucose] = liver cells breakdown glycogen to release glucose in blood. Skeletal muscle cells: use glycogen to breakdown into glucose and use glucose in glycolysis to produce atp for voluntary motion. The glucose obtained from glycogen can be used to produce e under anaerobic activity (no. *other sources of e like fa depend on o2 but glycogen can be broken down to glucose and produce e w/o using o2.

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