BCH 361 Lecture 9: Oxidative Phosphorylation

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brownbutterfly767

13 Feb 2017

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Glycolysis: glucose -> pyruvate + nadh + atp. Tca cycle: oxidize acetyl coa to extract e- and place them into nad+ and fad+. Etc: the carriers used to oxidatively phosphorylate adp to atp along etc. Nadh molecules formed via glycolysis and the nadh and fadh2 formed in tca are used to reduce o2 and generate atp molecules. Complex i accepts electrons from nadh and fadh2 and regenerate nad+. Electron movement creates electrical current which allows the proteins to act as h+ pumps and pump h+ from cytoplasm to intermembrane space. Once electrons reach complex iv, the electrons reduce o2 to form h2o. Once proton gradient created, atp synthase use the gradient to phosphorylate adp to atp. Conclusion: the oxidation of fuel molecules in glycolysis and the tca cycle is coupled to the oxidative phosphorylation of adp to atp by establishment of the h+ gradient along the etc.

Related Questions

The primary function of the electron transport chain and oxidative phosphorylation is which of the following?

A. to provide electrons and energy for the phosphorylation of ATP

B.to synthesize the reduced coenzymes necessary for digestion

C. to oxidize the reduced coenzymes NADH and FADH₂, and provide energy for the synthesis of ATP

D. to transport electrons from ATP to ADP, and synthesize acetyl CoA molecules

cerisewater-buffalo786

Fermentation occurs in the absence of oxygen, but O2 is not found in any of the reactions of glycolysis or fermentation. So, what drives these reactions at the level of glycolysis and fermentation? A. In the formation of ethanol, acetaldehyde accepts electrons from NADH, regenerating NAD+ B. ATP is synthesized in glycolysis, only if NAD+ is regenerated during fermentation C. Pyruvate donates electrons to NADH in lactic acid fermentation D. NADH synthesized in glycolysis is used to oxidize pyruvate to acetyl CoA during fermentation reactions E. In the formation of ethanol, pyruvate is decarboxylated in a reversible reaction, once oxygen is present again

teallizard787

After glycolysis and before the citric acid cycle (TCA), the pyruvate dehydrogenase complex breaks down the pyruvate to three separate components; a carboxyl group, a two-carbon fragment, and coenzyme A (CoA). What happens next to these products?

a. The carboxyl group is reduced and released as CO2, the two-carbon fragment is used to reduce NADH, and CoA is converted to acetyl CoA for the TCA.

b. The carboxyl group is oxidized and released as CO2, the two-carbon fragment is used to oxidize NAD+, and CoA is converted to acetyl CoA for glycolysis.

c. The carboxyl group is used to reduce NAD+, the two-carbon fragment is oxidized and released as CO2, and CoA is oxidized to acetyl CoA for oxidative phosphorylation the TCA.

d. The carboxyl group is oxidized and released as CO2, the two-carbon fragment is used to reduce NAD+, and CoA is converted to acetyl CoA for the TCA.

e. The carboxyl group is used to oxidize NAD+, the two-carbon fragment is reduced and released as CO2, and CoA enters the TCA.

BCH 361 Lecture 9: Oxidative Phosphorylation

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