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BLG 144 (97)
Ron Babin (38)
Lecture

digestive

2 Pages
68 Views

Department
Biology
Course Code
BLG 144
Professor
Ron Babin

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Absorption And Active Uptake Of The Products Of
Digestion In Small Intestine
Glucose
Absorbed by epithelial cells using a protein carrier
This protein carrier works by secondary active transport (co-transport system)
Glucose and Na+ are transported across the membrane into the intestinal cell
Further transport of glucose into blood capillaries by facilitated diffusion
NOTE: Fructose moves entirely by facilitated diffusion!
Amino Acids
Absorbed by epithelial cells by secondary active transport
Co-transport carrier proteins absorb amino acids and Na+ across the membrane
o Different carrier molecules transport different types of amino acids
o Carriers are associated with peptidase
Passes from the epithelial cells into capillaries by facilitated diffusion
Newborns don't produce trypsin, HCl → proteins are not digested before small intestine
is reached
o Whole proteins may be transported by endocytosis and exocytosis
o Uptake by endocytosis, release into blood by exocytosis
o Often occurs in newborns due to their immature mucosa
o Allows passage of antibodies from mother's milk - provides passive immunity for
the infant
o Accounts for many early food allergies as the protein is recognized as "foreign"
Lipids
Triglycerides digested into monogylcerate + glycerol + fatty acids by lipase
Monoglycerides combine with bile to form micelles
o 5mm in diameter / forms an emulsion / contains fatty acids and glycerol
Micelles move to membrane of epithelial cells
Monoglycerides + glycerol + fatty acids dissolve in bilayer
Triglycerides re-synthesise in cytoplasm / move into lymph capillaries (→lacteals)
Bile stays in small intestine
Oral Rehydration Therapy In The Control Of Gastro-
Intestinal Infections
High amounts of semi-liquid faeces result form toxins produced by microorganisms
o Toxins block Na+ channels in cells lining small intestine
o Stop reabsorption / conc. of Na+ ions in small intestine increases
o Water potential gradient is in the opposite way (into small intestine)

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Description
Absorption And Active Uptake Of The Products Of Digestion In Small Intestine Glucose  Absorbed by epithelial cells using a protein carrier  This protein carrier works by secondary active transport (co-transport system)  Glucose and Na+ are transported across the membrane into the intestinal cell  Further transport of glucose into blood capillaries by facilitated diffusion  NOTE: Fructose moves entirely by facilitated diffusion! Amino Acids  Absorbed by epithelial cells by secondary active transport  Co-transport carrier proteins absorb amino acids and Na+ across the membrane o Different carrier molecules transport different types of amino acids o Carriers are associated with peptidase  Passes from the epithelial cells into capillaries by facilitated diffusion  Newborns don't produce trypsin, HCl → proteins are not digested before small intestine is reached o Whole proteins may be transported by endocytosis and exocytosis o Uptake by endocytosis, release into blood by exocytosis o Often occurs in newborns due to their immature mucosa o Allows passage of antibodies from mother's milk - provides passive immunity for the infant o Accounts for many early food allergies as the protein is recognized as "foreign" Lipids  Triglycerides digested into monogylcerate + glycerol + fatty acids by li
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