ENH 222 Lecture Notes - Lecture 7: Fumonisin, Aflatoxin, Superantigen

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Toxins: ergotism toxic condition caused by growth of a fungus in grains, aflatoxins carcinogens produced in fungus-infected grains and nut products, fumonisins carcinogens produced in fungus-infected corn. Cardiotoxin: upera(cid:374)tige(cid:374): t(cid:455)pe i > i(cid:374)te(cid:374)se i(cid:373)(cid:373)u(cid:374)e respo(cid:374)se > (cid:272)(cid:455)toki(cid:374)es > fever, nausea, vomiting, shock (staph aureus, me(cid:373)(cid:271)ra(cid:374)e disrupti(cid:374)g to(cid:454)i(cid:374): t(cid:455)pe ii > l(cid:455)sis of (cid:272)ells (cid:271)(cid:455) disrupti(cid:374)g membrane, a-b toxins: type iii has two parts. A is active enzyme toxin that inhibits protein synthesis and kills cell. B binds to surface so toxin is transported across plasma membrane (clostridium) Intoxication (1 12 hrs: staphylococcus (infected food handler, bacillus (cooked rice, clostridium (produce, soil, e. coli (ground beef) Infection (6-72 hrs: salmonella (chicken, shigella (fecal contamination, campylobacter (chicken) https://www. youtube. com/watch?v=1ekehfkhwf4. 80/20 rule: 80% of quality problems caused by, 20%of (cid:272)o(cid:374)tri(cid:271)uti(cid:374)g fa(cid:272)tors k(cid:374)o(cid:449)(cid:374) as the (cid:862)(cid:448)ital fe(cid:449)(cid:863, others are k(cid:374)o(cid:449)(cid:374) as the (cid:862)tri(cid:448)ial (cid:373)a(cid:374)(cid:455)(cid:863) Designed to: prevent, reduce or eliminate potential biological, chemical and physical food safety hazards, including those caused by cross- contamination.

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