ENH 322 Lecture Notes - Lecture 4: Regulatory T Cell, Humoral Immunity, Epitope

122 views5 pages

Document Summary

Antibodies (ig/ab) and antigens: antibodies are also called immunoglobulins, glycoproteins in serum, produced by b cells, binds to immunogenic molecules- antigens (ag) Antibody binding specificity: antigens- many diff epitopes, antibodies- bind specifically to only one epitope of one pathogen. Monomer: 80% of serum antibodies in blood, lymph and intestine, 2ag binding sites, enhance phagocytosis, neutralize toxins and viruses, protects fetus and newborn, predominantly produced on subsequent exposue, half-life = 23 days. Igm antibodies: pentamer, 5-10% pf serum in antibodies in blood, lymph and on b cells, 10 ag binding sites, agglutinates microbes, half-life = 4 days first ab produced in response to infection. Iga antibodies: dimer in mucosal secretions w a secretory component, siga, monomer in serum, 10-15% of serum antibodies, 4ag binding sites, mucosal protection, half-life = 6 days in secretions. Igd antibodies in blood, lymph and on b cells: monomer, 0. 2% of serum antibodies, 2ag binding sites, on b cells, initiate immune response, half-life = 3 days.

Get access

Grade+20% off
$8 USD/m$10 USD/m
Billed $96 USD annually
Grade+
Homework Help
Study Guides
Textbook Solutions
Class Notes
Textbook Notes
Booster Class
40 Verified Answers
Class+
$8 USD/m
Billed $96 USD annually
Class+
Homework Help
Study Guides
Textbook Solutions
Class Notes
Textbook Notes
Booster Class
30 Verified Answers

Related Documents

Related Questions