ENH 322 Lecture Notes - Lecture 5: Varicella Vaccine, Smallpox Vaccine, Vaccinia
Document Summary
Killed vaccines: killed intact vaccines, poliomyelitis: inactivated polio virus produced in mammalian cell lines and formalin-inactivated, killed disrupted vaccines, treated with chemicals to remove certain components. Subunit vaccine: purified protein, pertussis: acellular purified antigens of b. pertussis only available on combo w other vaccines such as diphtheria and tetanus toxoids (dtap, purified polysaccharides. Invasive pneumococcal disease: capsular polysaccharide from strep pneumoniae (pneu) Inactivated toxin: diphtheria and tetanus: acellular diphtheria toxin detoxified w formaldehyde available as a prep absorbed w aluminum phosphate and combined w other toxoids, recombinant, hep b: purified hbsag produced from genetically engineered yeast (hb) Immunization of travelers: no single schedule for the administration of immunization s to travelers, each schedule must be personalized, will vary according to, age, existing medical conditions. Japanese encephalitis subunit: hep a, rabies, malaria: no vaccine available, chemoprophylactic drugs, and preventive measures. Immunoassays: elisa, polyclonal abs and mabs, agglurinarion. Ifa: nucleic acid tests, hybridization probes, pcr.