ENH 422 Lecture Notes - Lecture 5: Hepatitis B, Norovirus, Hbsag
17 Mar 2016
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Document Summary
Painful swelling of one or both paroid glands (below and in front of the ears) Most infecive during the irst 48 hours before the clinical symptoms. Viruses muliply and reach salivary glands through the blood. In combo with measles, mumps, rubella (mmr) Muliplies in epithelial lining of intestinal tract. Virus can someimes survive for days (like on cuing boards) Prevent by giving (hbig) hep b immune globin to new born. Acute hbv: infecions cannot be disinguished from other viral hep infecions. Chronic hbv: if hbsag persists longer than 6 months. Up to 10% of paients become chronic carriers. They are reservoirs for transmission of the virus/high rate of liver disease. Triggers an immune inlammatory response that either clears the infecion or destroys the liver. Capable of rapid geneic variaion to evade the immune system. Transmission: fecal-oral (from food and water and even aerosols from vomit) Diagnosis: serology tesing, stool samples, pcr and eia tests.
