NSE 22A/B Lecture Notes - Lecture 8: Fresh Frozen Plasma, Bone Marrow Suppression, Blood Transfusion
10 Sep 2019
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Nse22 fall week 8 part 2: blood transfusion therapy. Blood transfusion: intravenous administration of whole blood, its components, or a plasma- derived product for therapeutic purposes. Transfusion reaction: reaction that occurs d/t transfusion of mismatched blood. Ranges from mild response (i. e faintness, dizziness) to severe anaphylactic shock. 2 types: autologous transfusion: transfusion of own blood. Decrease risk (i. e mismatched blood, exposure to bloodborne infectious agents: allogeneic transfusion: transfusion of blood donated from someone else. Replace selected blood components (i. e clotting factors, platelets) * all blood products are only compatible with ns (except ivig) * don"t add drugs or additives to blood products. 7 types: whole blood (wb, packed rbcs (prbcs, platelets/thrombocytes, albumin, fresh frozen plasma (ffp, cyroprecipitate. Whole blood (wb): rbcs, wbcs, and platelets inside of plasma. Packed rbcs (prbcs): rbcs, preservative solution, and plasma. Platelets/thrombocytes: plasma proteins that allow clotting and regulate intravenous volume by maintaining plasma colloid osmotic pressure.
