OHS 322 Lecture Notes - Lecture 1: Anazarbus, Arrow Poison, Pedanius Dioscorides
30 Sep 2018
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Document Summary
Learning objectives: history of toxicology, basic concepts of exposure, basic concepts of dose, dose-response relationships. What is toxicology: the science of toxicology helps people from making informed decisions and balance. Toxicology is a multidisciplinary science, toxicology is both a qualitative and quantitative science. Different areas of toxicology: descriptive toxicology, mechanistic toxicology, regulatory toxicology: regulating for the government, is this ok is it not ok etc, environmental: effects of environmental toxic on people, economic, forensic, clinical. History of toxicology: antiquity, animal venoms and plant extracts of hunting, warfare, assassination, ebers papyrus (circa 1500 b. c. It is believed that the downfall to the roman empire was due to lead poisoning, because the lead was in a lot of what they ate, the armour they wore etc. Intro of new toxicants and antidotes: after ww2, delaney clause (1958; cancer in food products) gordon conference, Toxicology and applied pharmacology: society of toxicology (sot, national center for toxicologic research, epa, niehs.
