PLN 203 Lecture Notes - Lecture 3: Natural Killer Cell, Connective Tissue, Colony-Stimulating Factor

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White blood cells: are also called leukocytes and do not have hemoglobin. However, white blood cells do have nuclei and other organelles. Most white blood cells are in connective tissue proper and lymphatic system organs. There is a small number of wbc in the blood approx. Loose connective tissue more ground substance, fewer fibers, for example, fat (adipose tissue) Dense connective tissue more fibers, less ground substance, for example tendons. Four characteristics of circulati(cid:374)g wbc"s: can migrate out of bloodstream, have amoeboid movement, attracted to chemical stimuli (positive chemotaxis) toward a higher concentration of the chemical, some are phagocytic neutrophils, eosinophils and monocytes. Prolong exercise causes a temporary suppression of immune function neutrophils bust, increase in lymphocytes and monocyte antigens. Very active, first to attack bacteria (increase) Defensins (peptides from lysosomes) attack pathogen membranes. Control inflammation with enzymes that counteract inflammatory effects neutrophils and mast cells. Are less than 1% of circulating wbcs.

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