Class Notes (1,000,000)
CA (620,000)
Seneca (1,000)
(200)
rupi (10)
Lecture 8

Nursing NUR304 Lecture Notes - Lecture 8: Tachycardia, Spironolactone, Amlodipine


Department
Nursing
Course Code
Nursing NUR304
Professor
rupi
Lecture
8

This preview shows page 1. to view the full 4 pages of the document.
Chapters 24. 25 & 26 Antihypertensive Drugs
Drug/Classificati
on
Mechanism of
Action
Common Adverse
Effects
Drug Interactions Nursing Interventions
furosemide
Produces diuresis,
lowers B/P
Enhances excretion
of NaCl, K at the
ascending loop of
Henle
Vigorous diuresis
may lead to
profound water
loss/electrolyte
depletion, resulting
in hypokalemia,
hyponatremia,
dehydration
Ototoxicity,
exacerbate diabetes
Amphotericin B,
nephrotoxic,
ototoxic
medications.
Medications causing
hypokalemia.
Monitor B/P, vital signs, I/O,
weight. Note extent of
diuresis. Watch for changes
from initial assessment.
Hypokalemia may result in
tremors, muscle cramps,
changes in strength, altered
mental status, cardiac
arrhythmias. Hyponatremia
may result in cold clammy
skin, thirst, confusion.
spirono-lactone
Produces diuresis,
lowers B/P
Promote sodium and
water excretion by
inhibiting aldosterone
in distal tubule;
potassium sparing
Severe hyperkalemia
may produce
arrhythmias,
bradycardia, EKG
changes
ACE inhibitors,
potassium
supplements,
potassium
containing
medications.
May increase half-
life of digoxin.
NSAIDs may
decrease
antihypertensive
effect
Monitor serum electrolyte
level for increased
potassium, BUN, creatinine.
Monitor B/P
Monitor for hyponatremia
(confusion, cold/clammy
skin, thirst, dry mouth)
Monitor for hyperkalemia
(diarrhea, muscle twitching
followed by
weakness/paralysis,
arrhythmias)
Obtain daily weight.
Note changes in edema, skin
turgor
hydrochloro-
thiazide
Promotes
diuresis, reduces
B/P,
antihypertensive
Diuretic: Blocks
reabsorption of water,
sodium, potassium at
distal tubule.
Antihypertensive:
Reduces plasma,
extracellular fluid
volume, peripheral
vascular resistance by
direct effect on blood
vessels
Vigorous diuresis
may lead to
profound water
loss/electrolyte
depletion, resulting
in hypokalemia,
hyponatremia,
dehydration
Acute hypotensive
episode may occur
Hyperglycemia may
occur during
prolonged therapy
May increase risk of
digoxin toxicity
associated with
hydrochlorothiazide
induced
hypokalemia
Monitor BP, vital signs,
electrolytes, I/O, daily
weight.
Note extent of diuresis.
Watch for changes from
initial assessment.
Hypokalemia may result in
tremors, muscle cramps,
changes in strength, altered
mental status, cardiac
arrhythmias. Hyponatremia
may result in confusion,
cold/clammy skin, thirst, dry
mouth.
Be especially alert for
potassium depletion in pts
taking digoxin.
You're Reading a Preview

Unlock to view full version