APMA 912 Lecture Notes - Lecture 13: Submucosa, Migrating Motor Complex, Chymotrypsin

• School: Simon Fraser University
• Department: Applied & Comp Math
• Course: APMA 912
• Professor: fril

Document Summary

Acid secre2on regula2on k&s fig 28- 10. Secre2on protec2ve mucus k&s fig 28- 2a, 5, & 11. Slow waves in res2ng membrane poten2al. K&s 28- 13 & g&h 62- 3. K&s fig 28- 14 breaking it down k&s fig 29- 20. Alterna2ng contrac2on and relaxa2on result in con2nuous mixing of contents so surfaces of contents are exposed to enzymes. Clench et al ajp 256: g598. Record starts at top le with most proximal electrode . Prolonged, rhythmic bursts of ac2on poten2als (and resul2ng contrac2ons) slowly travel downstream. Electrical ac2vity (shown) causes mechanical ac2vity, contrac2on, that progressively sweeps the luminal contents downstream. Mmc occurs largely when gut is empty (no food, only secre2ons and bacteria). Orienta2on: accessory organs g&h 64- 11. K&s fig 29- 2 pancrea2c secre2ons k&s table 29- 1, fig 29- 12. Pancrea2c exocrine secre2on: local & systemic inputs. K&s figs 29- 5 & 6. K&s fig 29- 3&4 regula2on of pancrea2c secre2on g&h fig 64- 9, 10.