BISC 101 Lecture Notes - Lecture 1: Intermediate Filament, Tight Junction, Lipid Bilayer

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(cid:862)(cid:272)ells are as fu(cid:374)da(cid:373)e(cid:374)tal to li(cid:448)i(cid:374)g s(cid:455)ste(cid:373)s as ato(cid:373)s are to (cid:272)he(cid:373)istr(cid:455)(cid:863) (cid:862)the si(cid:373)plest (cid:272)olle(cid:272)tio(cid:374) of (cid:373)atter (cid:272)a(cid:374) (cid:271)e ali(cid:448)e(cid:863: key concepts: Two basic cell designs: prokaryotic and eukaryotic. Structure of individual cell components is closely related to function. Eukaryotic cells have extensive membrane-bound organelles with specialized, compartmentalized functions. Cytoskeleton: network o f fibres organises internal structure and regulates activities of cell. Connections between cells (eg: gap junctions, tight junctions) coordinate cell activities. Cells are very dynamic, always building up/breaking up materials: prokaryotic vs. eukaryotic cells. Bacteria and archaea = prokaryotes: ha(cid:448)e (cid:862)si(cid:373)pler(cid:863) (cid:272)ell stru(cid:272)ture (cid:894)lack a membrane-bound nucleus) Both cell types have plasma membrane, cytoplasm, genetic material (dna), ribosomes. Cytosol: cytoplasm liquid component, cytoplasm: cytosol + organelles. Prokaryotes: single, circular chromosome (dna molecule) in non-membrane bound nucleoid. Tough fibrous cell wall (different material than plant cells) Prokaryotes have only a few proteins, but there are ~20-30 in eukaryotes: generalized eukaryotic animal cell.

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