BPK 142 Lecture Notes - Lecture 7: Arteriovenous Oxygen Difference, Globin, Sildenafil
Document Summary
Pulmonary structure and function: anatomy of the respiratory system. Consists of nose, pharynx, larynx, trachea, bronchi, and lungs (conducting airways, alveoli, blood vessels, elastic tissue) Bronchi primary, secondary, and tertiary bronchi terminal and respiratory bronchioles alveolar ducts alveoli. With branching, supportive cartilage is gradually replaced by smooth muscle. Contraction/relaxation of smooth muscle, constricts/dilates bronchioles affects airway resistance. Volume of conducting airways = anatomic dead space (vd) 150 ml. Alveoli: small, thin walled sacs with capillary embedded walls; site of gas (o2 & co2) exchange between air and blood: conducting airways lead inspired air to the alveoli. Mechanics of breathing gas = a x d x (p1 p2) T2: pt = p1 + p2 + p3 + . Dalton"s law: total pressure of a gas mixture is the sum of individual gas pressures. Molecules move from areas of higher pressure to areas of lower pressure.