BPK 375 Lecture Notes - Lecture 11: Lipoprotein Lipase, Subcutaneous Tissue, Lipid Droplet
24 Nov 2016
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Document Summary
Bpk 375 unit 8 week 11 growth & development of adipose tissue & the estimation of % White adipocytes have a scant ring of cytoplasm surrounding a single large lipid droplet. They have flattened nuclei which are eccentric within the cell. Their major role is in glucose, fatty acid, lipoprotein & cholesterol metabolism. They are found in subcutaneous and internal adipose tissue deposits. Brown adipocytes are polygonal in shape, considerable volume of cytoplasm and contain multiple lipid droplets of varying size. Their nuclei are round and almost centrally located. Has uncoupling protein (ucp) found in the mitochondria which gives it the thermogenic properties, related to thermoregulation and metabolism. Brown adipose tissue is most prominent in newborn animals. In human infants it comprises up to 5% of body weight, then diminishes with age to virtually disappear by adulthood. Brown adipose tissue (bat) has uncoupling protein (ucp) found in the mitochondria which gives it the thermogenic properties.
