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Class Notes for Department of Humanities Biological Sciences at Simon Fraser University

BISC 313 Lecture 6: Lecture 06, Jan 18
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Five factors - Quantity, persistence, bioaccumulation, toxicity o Toxicity is country dependent, have their own threshold (LC50 value) - Other endpoints that we consider to be inherently toxic (IT) o mutagenic, cause alter...

Department of Humanities Biological Sciences
BISC 313
Chris Kennedy
BISC 313 Lecture 8: Lecture 08, Jan 23
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Key characteristics Fate 1) Tendency to be hydrophobic a. PBT assessments i. For the B assessments, use log Kow, or better use BCF, or even better BAF ii. BAF better bc there are multiple sources (water + diet, etc) 2) Che...

Department of Humanities Biological Sciences
BISC 313
Chris Kennedy
BISC 313 Lecture Notes - Lecture 7: Botulinum Toxin, Nicotine, Caffeine
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Lecture 01: Jan 7 , 2019 What is toxicology? - Very different things to different people - Toxicology: The Basic Science of Poisons o Problem: Botulinum toxin, dioxins, nicotine, alcohol, heavy metals, caffeine, salt, wate...

Department of Humanities Biological Sciences
BISC 313
Chris Kennedy
BISC 313 Lecture Notes - Lecture 5: Bioconcentration, Bioaccumulation, Xenobiotic
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Five factors for categorization 1) Quantity 2) Persistence 3) Bioaccumulative - Bioaccumulation is a process by which organisms uptake foreign chemicals - Increase body burdens o Reach toxic thresholds Bioaccumulation - Ac...

Department of Humanities Biological Sciences
BISC 313
Chris Kennedy
BISC 313 Lecture Notes - Lecture 3: Lake Apopka, Endocrine Disruptor, Toxicology
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Lecture 03, Jan 11 History - Foreign chemicals (exogenous), xenobiotic - Middle ages o Borgias, kept arsenic in his ring - Catherine de medici o first experimental toxicologist o studied poisons, remedies, medicines admini...

Department of Humanities Biological Sciences
BISC 313
Chris Kennedy
BISC 313 Lecture 2: Lecture 02, Jan 9
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Lecture 2, Jan 9 Goal - Enhancement of quality of life and protection of the environment - End result of toxicological studies: o Protect human health + environment o Develop new and useful agents (eg. pesticides, food add...

Department of Humanities Biological Sciences
BISC 313
Chris Kennedy
BISC 313 Lecture 4: Lecture 04, Jan 14
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Lecture 04, Jan 14 Environmental Chemicals (Env Fate) - 60K 100K commonly used o Priority pollutant lists o More information Potential problems Humans Environment - Most countries have chemical management plans o Quite rec...

Department of Humanities Biological Sciences
BISC 313
Chris Kennedy
BISC 333 Lecture 1: Why Study Developmental Biology
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Developmental biology is the study of how organisms become what they are. This lecture: 1) Why study developmental biology? 2) Course information tutorials, grading scheme, and exam policies. 3) Introduction to study of de...

Department of Humanities Biological Sciences
BISC 333
Sherryl Bisgrove
BISC 333 Lecture 2: Introduction to Developmental Biology
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Introduction to Developmental Biology How does a single cell, the fertilized egg (or zygote), give rise to a complex, multicellular organism? Developmental biologists are interested in understanding how these processes are...

Department of Humanities Biological Sciences
BISC 333
Sherryl Bisgrove
BISC 316 Lecture 4: lab 4 skull & jaws

Biological Sciences 316 Vertebrate Biology 1187 Laboratory Session 4 Skulls and Jaws of Vertebrates Introduction a. The head skeleton of vertebrates is complicated both in origin and structure. It has three broad component...

Department of Humanities Biological Sciences
BISC 316
Tammy McMullan
BISC 100 Lecture Notes - Lecture 19: Germination, Semelparity And Iteroparity, Biogeography

Ecology Ecology: the scientific study of interactions btw organisms environment Biosphere > Ecosystem > Community > Population 3 different types of Species Dispersion (the manner in which individuals in a popu are dispers...

Department of Humanities Biological Sciences
BISC 100
Onkar Bains
BISC 100 Lecture Notes - Lecture 12: Oxidative Phosphorylation, Intermembrane Space, Citric Acid Cycle

Cellular Respiration The parts of the mitochondria Matrix Cristae intermembrane space oxidation o reducing agent reduction oxidizing agent 3 parts of cellular respiration locations o Glycolysis o citric acid cycle (Krebs ...

Department of Humanities Biological Sciences
BISC 100
Onkar Bains
BISC 100 Lecture Notes - Lecture 1: Homeostasis, Organelle, Organism

Diversity of Life and Scientific Method 7 Properties of Life o Order o Response to Environment o EvolutionaryAdaptation o Homeostasis o Reproduction o Growth Development o Energy Processing Levels of Biological Organizati...

Department of Humanities Biological Sciences
BISC 100
Onkar Bains
BISC 100 Lecture Notes - Lecture 15: Human Serum Albumin, Molecular Cloning, Molecular Sieve

recombinant DNA: nucleotide sequences from 2 dierent sources are combined in vitro into the same molecule DNA cloning: make genesized pieces of DNA into identical copies, using bacteria and their plasmids DNA plasmid: smal...

Department of Humanities Biological Sciences
BISC 100
Onkar Bains
BISC 100 Lecture Notes - Lecture 16: Allele Frequency, Genetic Drift, Disruptive Selection

population genetics: study of how population change genetically over time gene frequency change = population has evolved microevolution : change in allele frequencies in population over generations population: a localized ...

Department of Humanities Biological Sciences
BISC 100
Onkar Bains

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