HSCI 216 Lecture Notes - Lecture 9: Chronic Kidney Disease, Birth Weight, Umbilical Cord
Document Summary
Perinatal problems (5 months before to 1 month after birth) Constant growth requires a longer period of time. Time to learn during childhood to adolescence. Growth is quantitative: height, weight, size and shape, cell division, for limited period. Inauterine growth retardation: fetus is smaller than expected for gestational age, when estimated fetal weight is <10th percentile: thin, pale, loose, dry skin; thin and dull looking umbilical cord. Proximate maternal factors: high blood pressure, chronic kidney disease, advanced diabetes, heart or respiratory diseas, malnutrition, anemia, infection, substance abuse (alcohol, drugs, cigarette smoking. Factors involving the uterus and placenta: decreased blood flow in uterus and placenta, placenta abruption (detachment of placenta from uterus, placenta previa (low attachment of placenta to uterus) Factors related to the developing baby (fetus: multiple gestation (twins, triplets, etc, infection, birth defects and chromosomal abnormality. Early onset, ultimate causes: chromosomal abnormalities, maternal disease or severe placental problems; problematic maternal fetal interactions.