HSCI 100 Lecture Notes - Lecture 10: Bone Marrow, Antibody, Thermoregulation

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Transportation: o2 brought to tissues (atp), nutrients to build proteins, remove wastes, co, hormones etc. Regulatory functions: body temperature (thermoregulation), water-salt balance, body ph. Formed elements 45%: from cells produced in red bone marrow. Plasma 55%: 92% water and 8% salt and organic molecules. Albumins: most abundant + important for osmotic pressure + transportation of other molecules. Used for blood typing + vaccines: vaccines stimulate antibodies. Process for the blood stem cell differentiating into diff. descendants. Stem cell: ability to differentiate into different kinds of cells. In red bone marrow, stem cells divide into blood cells. Contains hemoglobin molecules (protein: binds 4 o2. Iron atoms is the place that binds to oxygen. Erythropoietin (epo) is excreted by kidney cells: moves to red marrow when o2 levels are low. Anemia: too few rbc or hemoglobin = causes low energy levels. Sickle-cell anemia: genetic disease causing rbc to be sickle shaped (tends to rupture)

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