HSCI 100 Lecture Notes - Lecture 6: Neuromuscular Junction, Action Potential, Myofibril

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Attachments: tendon connective tissue that connects muscle to bone, origin attachment of a muscle on a stationary bone, insertion attachment of a muscle on a bone that moves. Action: antagonistic muscles that work in opposite pairs, synergistic muscles working in groups for a common action, note the only force muscles exert is by pulling (contracting) Visualizing skeletal muscles: (a myofibril has many sacromeres) Made of two main proteins: myosin: composes the thick filaments shaped like a golf club. Myosin is a motor protein that uses the energy in atp to create movement: actin: composes the thin filaments (microfilaments) These filaments slide over one another during muscle contraction. Troponin ca2+ complex pulls tropomyosin away, exposing myosin binding sites. The role of myosin and atp in muscle contraction: Fuel sources for muscle contraction: in the muscle: Fatty acids (all will be converted to atp)

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