HSCI 211 Lecture Notes - Lecture 6: Centroacinar Cell, Adipose Tissue, Glycogenesis
16 Apr 2016
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Overview: diabetes is caused by an excess of glucose in the blood, the level of glucose in the blood is determined by: The amount of glucose that insulin (facilitates) can remove from the blood. (if the blood sugar level is too low), the ability of glucagon to increase blood glucose levels: we get glucose from carbs, glucose regulation: balance between the action of insulin (uptaker) and glucagon. Primary fuel source for the brain, gonads and retina. Humans: glycogen (found in liver, adipose tissue, skeletal muscle) Secrete enzymes into the lumen of the intestine (out of the body) Beta cells (80% of the islet) secrete insulin. Insulin increases the uptake of glucose into tissues (liver, muscle, adipose cells: liver. Extra is converted to fat: adipose tissue. Free fatty acids in the blood inhibits glucose uptake by the cells. Lipase releases free fatty acids into the blood.
