HSCI 212 Lecture Notes - Lecture 1: Epidemiology, Immunology, Carlo Urbani

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Course intro: learning objectives: describe the general role of the causal model in disease transmission. Diseases are spread and manifested through a complex interplay; status of one may affect another and determine whether a disease spreads or not. If maintained in a state of equilibrium, a state of health within the human host is maintained. Study questions: explain the difference between a disease and an infectious disease. Disease: disorder of structure or function in a human, animal, or plant especially one that produces specific symptoms, or affects a specific location and isn"t simply a direct result of physical injury. Host: individual human in whom the agent produces disease; intrinsic traits influence the risk of exposure, susceptibility once exposed, and the responses to casual factors. Agent: factor whose presence or absence can cause disease; necessary for disease to occur *microbes*; infectivity, pathogenicity, virulence, immunogenicity. Suggest a couple of environmental factors that could affect transmission.

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