HSCI 212 Lecture Notes - Lecture 8: Reverse Transcriptase, Envelope Glycoprotein Gp120, Dendritic Cell
19 Oct 2015
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Lecture 8 gp120 gp 41- proteins that mediate the infection. critical for allowing the virus to attach and infect a cell. very important vaccine target. carries along with it the reverse transcriptase enzyme: key functional units that gives. Hiv affects certain cells. depends on receptor on surface called cd4. Dna that encodes hiv genome goes to nucleus and gets inserted into host dna by. Hiv rna synthesizes hiv proteins and butt off the cell and take host cell membrane with it which is where it gets its envelope. Mutation rate is high: has to do with reserve transcriptase that makes mistakes all the time. Latency period: pro virus present in host genome and not doing anything. takes long time for it to become active. Sexual contact: male to male, male to female, female to male, even female to female. Blood exposure: sharing needles, occupational exposure, transfusion of blood products (blood products weren"t being screened, and would receive transmissions with.
