HSCI 216 Lecture Notes - Lecture 11: Triceps Brachii Muscle, Diabetes Mellitus Type 1, Menarche
11 Sep 2017
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To identify the hormones other than sex steroids that are associated with puberty. To discuss the roles of those hormones during puberty. To describe the anatomical changes that occur during puberty (separate from maturity of the sexual organs) Also regulated by the hypothalamus via release of growth hormone releasing hormone (ghrh) and somatostatin (ss) Act on the pituitary to regulate the release of growth hormone (gh) Gh stimulates the release of insulin like growth factors (igfs) from the liver and other tissues. Gh and igf-1 stimulate skeletal growth and protein anabolism. Increased activity in the somatropic axis is a normal part of pubertal development: increase in somatropic activity appears to be a consequence of gonadal steroid production, estrogen, testosterone, both affect gh production by changing amplitude of those. What controls the increase in activity in the somatotropic axis? (answered above) Hypothalmus ghrh + ss pituitary gh liver & other tissues igf-1.
