HSCI 216 Lecture Notes - Lecture 3: Epigenome, Chromatin Remodeling, Divergent Evolution

• School: Simon Fraser University
• Department: Health Sciences
• Course: HSCI 216
• Professor: Pablo Nepomnaschy

Document Summary

Physical barriers will cause mutations to occur. If selective forces on different sides of the river, the two populations because of mutations eventually will become 2 different species. But if you have a bridge, the 2 populations will cross breed. Clarifying: mendel"s law and where your sitting spot . The explanation of the sitting spot corresponds to the law of independent assortment: traits coded by genes located on different chromosomes are inherited independently. Not to me(cid:374)del"s (cid:862)la(cid:449) of segregatio(cid:374)(cid:863: members of each pair of factors (alleles) controlling a trait in an individual separate into separate haploid gametes. Epigenome: set of chemical marks in an individual"s genome that affects gene expression. This set of marks is heritable but can be modified by environmental exposures. Analogy: epigenome are the switches on and off, either prevent of allow a specific dna to code for a specific protein. Why is the epigenome necessary for development: cell differentiation.